Absence of a Direct Anabolic Effect of 17 β-Estradiol on Normal Human Bone Marrow Stromal Cells

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Absence of a Direct Anabolic Effect of 17 β-Estradiol on Normal Human Bone Marrow Stromal Cells

The effects of 17 beta-estradiol on the proliferation and differentiation of cultured normal human bone marrow stromal cells were investigated. Treatment of 17 beta-estradiol at the concentration of 10(-6) approximately 10(-10) M for either 48 hours or 7 days did not affect [3H] thymidine incorporation. 17 beta-estradiol (10(-8)M) treatment for 4 or 7 days also failed to stimulate alkaline phos...

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ژورنال

عنوان ژورنال: The Korean Journal of Internal Medicine

سال: 1994

ISSN: 1226-3303,2005-6648

DOI: 10.3904/kjim.1994.9.1.14